contributed talk given at RNA Club 2025, Prague, Czechia
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Primordial interactions between RNA and short peptides
Michal Kolář
Left: interface between protoribosomal RNA and short fragments of r-protein uL22
Petrov et al.: History of the ribosome and the origin of translation PMID 26621738
Kovacs et al.: Frozen in time: the history of proteins PMID 28201543
Kolář, Hlouchová: Evolution of protein-RNA interactions PMID 40628174
take this home:
Peptides stabilize ancestral ribosomal RNA (and promote protoribosome aggregation).
Rudolf's poster #21